106Asclepius

www.heartland.org FDA Study: Cancer Risks Nearly Nil for 1-2 Cigars Per Day

The FDA, which now regulates cigars, has taken the position that “cigar smoking carries many of the same health risks as cigarette smoking.”

107AsclepiusIf you are going to smoke tobacco, use a pipe or cigar. If you are going to use smokeless tobacco, use snuff or snus.

'Based on available evidence, for chewing tobacco RRs were significantly higher than one for oral cancer and oesophageal cancer, while for snus or snuff we did not find sufficient evidence of a RR greater than one for any health outcome.' - Lancet 2017; 390: 1084–1150

'Nasal snuff and snus were not associated with oral cancer risk.' - DOI: 10.1093/ntr/nty074

108AsclepiusCigarettes are in general pretty gross. I don't recommend getting your nicotine from cigarettes, at least not primarily. Just look what goes into these things
www.youtube.com/watch?v=pPtCZawoIbw

109Asclepius>>108
If you are going to smoke cigarettes, don't use filtered cigarettes. Filters cause lung cancer.

"While the application of filter ventilation can result in lower machine-measured tar yields, the composition of the smoke changes increases tobacco toxicant yields and adverse biological effects as follows"

"Among the increased toxicants was (N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK), a potent lung carcinogen, in agreement with other published studies (57,64,68–72)"

"Filter ventilation statistically significantly increased the mutagenicity of tar independent of other cigarette designs and tobacco formulations"

www.ncbi.nlm.nih.gov Cigarette Filter Ventilation and its Relationship to Increasing Rates of Lung Adenocarcinoma

The 2014 Surgeon General’s Report on smoking and health concluded that changing cigarette designs have caused an increase in lung adenocarcinomas, implicating cigarette filter ventilation that lowers smoking machine tar yields. The Food and Drug ...

110AsclepiusIn the Surgeon General’s 1964 report on smoking and health, pipe smokers who inhaled had the same mortality rate as cigarette smokers (not great), while pipe smokers who reported to never inhale actually had lower mortatliy rates than never-smokers. There is nothing wrong with smoking cigars and pipes

www.esquire.com The Oldest Man in America Is 112 and Smokes 12 Cigars a Day

He also loves a good whiskey and coke.

111AsclepiusThere is a long laundry list of cognitive benefits from nicotine use. Faster reaction times, better working memory, etc. Besides that it can help treat mental illnesses, parkinsons, and alzheimers.

pubmed.ncbi.nlm.nih.gov Meta-analysis of the acute effects of nicotine and smoking on human performance - PubMed

The significant effects of nicotine on motor abilities, attention, and memory likely represent true performance enhancement because they are not confounded by withdrawal relief. The beneficial cognitive effects of nicotine have implications for initiation of smoking and maintenance of tobacco depend …

112AsclepiusThis study from South Korea found smokers 67% less likely to be infected with SARS-CoV-2. In comparison, the J&J vaccine is 66.3% effective. There were similar studies out of China and France

113AsclepiusWhen reading any animal studies about smoke, remember that neanderthals and modern humans have specific adaptations to tolerate smoke, as we have been sitting around fires for a very long time

phys.org Genetic research reveals Neanderthals could tolerate smoke

The idea that modern humans displaced Neanderthals because they were better protected against toxic smoke components is now under fire. An earlier study that put forward this suggestion has now been refuted by genetic research by scientists from Leiden and Wageningen. This new research was published in Molecular Biology and Evolution on 24 November.

114anthonyFrom the first link:
>Next up, the results of the Whitehall study went like this: people who gave up smoking showed no improvement in life expectancy; there were also no changes in deaths caused by heart disease, lung cancer, or other causes. The only exception was that certain types of cancer were more than twice as common in people who gave up smoking.

A link between giving up smoking and cancer is interesting. Reminds me of some stuff Gabor Mate wrote about smoking in one of his books. He doesn't endorse cigarettes but suggested that while unhealthy the big deciding factor in whether they're just kind of bad for you or whether they destroy you with cancer was personality and lifestyle based. Cited an old study on smokers within a community in Yugoslavia which everyone worked the same industry.

>

"If smoking caused lung cancer, every smoker
would develop the disease.
Several decades ago, David Kissen, a British chest surgeon,
reported that patients with lung cancer were frequently
characterized by a tendency to “bottle up” emotions. 1 In a number
of studies, Kissen supported his clinical impressions that people with
lung cancer “have poor and restricted outlets for the expression of
emotion, as compared with non-malignancy lung patients and
normal controls.” 2 The risk of lung cancer, Kissen found, was five
times higher in men who lacked the ability to express emotion
effectively. Especially intriguing was that those lung cancer patients
who smoked but did not inhale exhibited even greater repression of
emotion than those who did. Kissen’s observations implied that
emotional repression works synergistically with smoking in the
causation of lung cancer. The more severe the repression, the less
the smoke damage required to result in cancer.

Kissen’s insights were confirmed in spectacular fashion by a
prospective study German, Dutch and Serbian researchers conducted
over a ten-year period in Cvrenka, in the former Yugoslavia. The
purpose of the study was to investigate the relationship of
psychosocial risk factors to mortality. Cvrenka, an industrial town of
about fourteen thousand inhabitants, was chosen partly because it
was known to have a high mortality rate and partly because its
stable population base permitted easier follow-up."

Nearly 10 per cent of the town’s inhabitants were selected, about
one thousand men and four hundred women. Each was interviewed
in 1965–66, with a 109-item questionnaire that delineated such risk
factors as adverse life events, a sense of long-lasting hopelessness
and a hyper-rational, non-emotional coping style. Physical
parameters like cholesterol levels, weight, blood pressure and
smoking history were also recorded. People with already diagnosed
disease were excluded from the research project.

By 1976, ten years later, over six hundred of the study
participants had died of cancer, heart disease, stroke or other
causes. The single greatest risk factor for death—and especially for
cancer death—was what the researchers called rationality and anti-
emotionality, or R/A. The eleven questions identifying R/A
measured a single trait: the repression of anger. “Indeed cancer
incidence was some 40 times higher in those who answered positively to
10 or 11 of the questions for R/A than in the remaining subjects, who
answered positively to about 3 questions on average…. We found
that smokers had no incidence of lung cancer unless they also had
R/A scores of 10 or 11, suggesting that any excect of smoking on the
lung is essentially limited to a ‘susceptible minority.’” 3

These findings do not absolve tobacco products or cigarette
manufacturers of responsibility in the prevalence of lung cancer—on
the contrary. All the thirty-eight people in the Cvrenka study who
died of lung cancer had been smokers. The results indicated that for
lung cancer to occur, tobacco alone is not enough: emotional
repression must somehow potentiate the effects of smoke damage on
the body. But how?

>

Goes on to talk a lot more about the relationship between emotional life and susceptibility to bodily harm and damage of all kinds, an idea which i think will inevitably mainstream and be one of the big things that really kills conventional modern medicine practice.

116Hank>>114
this isn't true
www.futuremedicine.com/doi/full/10.2217/epi-2016-0001
we know that quitting smoking is reflected in the methylome
but as this study confirms, some signatures never return to never smoker levels - www.ahajournals.org/doi/full/10.1161/CIRCGENETICS.116.001506

117monadic>>116
signatures, but what of actual outcomes?

>>114
fuck, I always repress anger

128Asclepius

204Anonymous

205Anonymous>>204

pubmed.ncbi.nlm.nih.gov Nicotinic Acetylcholine Receptors Modulate Bone Marrow-Derived Pro-Inflammatory Monocyte Production and Survival - PubMed

It is increasingly clear that nicotinic acetylcholine receptors (nAChRs) are involved in immune regulation, and that their activation can protect against inflammatory diseases. Previous data have shown that nicotine diminishes the numbers of peripheral monocytes and macrophages, especially those of …

522Anonymous

561AnonymousTobacco users had lower rates of gyno than the control

636monadicthe entire idea that second hand smoke is dangerous was actually a lie

"The updated science debunks the alarmist fantasies that were used to sell smoking bans to the public, allowing for a more sober analysis suggesting that current restrictions on smoking are extreme from a risk-reduction standpoint."

slate.com Secondhand Smoke Is Not Nearly As Dangerous As We Thought. Shouldn’t That Matter?

Helena, Montana, does not often make global headlines, but in 2003 the small capital city became known for briefly achieving one of the most astounding...

637monadic

link.springer.com Cigarette smoking is associated with higher thyroid hormone and lower TSH levels: the PREVEND study

Endocrine - The extent to which smoking is associated with thyroid stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) when taking account of clinical variables...

638monadic>>637
New studies have shown that smoking may protect against the development of thyroid peroxidase antibodies, which may result in a decreased risk of Hashimoto’s hypothyroidism (HH), whereas it stimulates the development of Graves’ hyperthyroidism (GH)

eje.bioscientifica.com Smoking and autoimmune thyroid disease: the plot thickens

New studies have shown that smoking may protect against the development of thyroid peroxidase antibodies, which may result in a decreased risk of Hashimoto’s hypothyroidism (HH), whereas it stimulates the development of Graves’ hyperthyroidism (GH). According to the above-mentioned hypothesis, to stop smoking would decrease the risk of GH but increase the risk of HH. Also, smoking has been identified as one of the risk factors for the development or worsening of eye changes after 131I treatment of GH. Additionally, the outcome of medical treatment of Graves’ ophthalmopathy (GO) is less favourable in smokers as compared to non-smokers. There is concern also about the effect of passive smoking on autoimmune thyroid disease. In a recent study it has been shown that the latter may have a deleterious effect on childhood GO.